产品编号
产品名称
产品包装
产品价格
S1842-1mg
Rapamycin (FRAP/mTOR抑制剂)
2mg/ml×0.5ml
313.00元
S1842-5mg
Rapamycin (FRAP/mTOR抑制剂)
5mg
370.00元
S1842-25mg
Rapamycin (FRAP/mTOR抑制剂)
25mg
838.00元
S1842-100mg
Rapamycin (FRAP/mTOR抑制剂)
100mg
1653.00元
S1842-500mg
Rapamycin (FRAP/mTOR抑制剂)
500mg
5202.00元
Rapamycin也称AY 22989或sirolimus，可与FKBP12形成复合物，随后结合并抑制FRAP/mTOR。mTOR是哺乳动物中rapamycin的作用靶点，也被称为FRAP或FAFT，是一个Ser/Thr蛋白激酶，可以激活p70 S6 kinase。Rapamycin对于p70 S6 kinase的抑制作用的IC50为0.05nM。Rapamycin通过抑制FRAP/mTOR可以抑制p70 S6 kinase的磷酸化和激活，抑制4E-BP1/PHAS1的磷酸化并促进其对eIF4E的结合和抑制。
Rapamycin分子量为914.17，分子式为C51H79NO13，CAS Number：53123-88-9。本产品纯度大于98%。
本Rapamycin 2mg/ml包装产品用DMSO配制，共0.5ml。5mg，25mg，100mg和500mg包装为粉末装。
包装清单：
产品编号
产品名称
包装
S1842-1mg
Rapamycin (FRAP/mTOR抑制剂)
2mg/ml×0.5ml
S1842-5mg
Rapamycin (FRAP/mTOR抑制剂)
5mg
S1842-25mg
Rapamycin (FRAP/mTOR抑制剂)
25mg
S1842-100mg
Rapamycin (FRAP/mTOR抑制剂)
100mg
S1842-500mg
Rapamycin (FRAP/mTOR抑制剂)
500mg
—
说明书
1份
保存条件：
-20℃避光保存，半年有效。
注意事项：
本产品对人体有害，操作时请小心，并注意有效防护以避免直接接触人体或吸入体内。
本Rapamycin在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内，可以20-25℃水浴温育片刻至全部融解后使用。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
使用说明：
1. Rapamycin常见使用浓度范围为10-100nM。具体的最佳工作浓度请参考相关文献，或根据实验目的，以及所培养的特定细胞和组织，通过实验进行摸索和优化。
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自噬
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